NuNaf Tablets

Salen Capsules / Topical Solution (Methoxsalen Capsules U.S.P. Methoxsalen Topical Solution U.S.P. 1% w/v) Back

NuNaf Tablets

Composition: Salen Capsules
Each hard gelatin capsule contains
Methoxsalen U.S.P    10 mg
Excipients    q.s.
Color    Approved colour used in Empty Capsule Shell

Composition: Salen Topical Solution
Methoxsalen U.S.P.    1% w/v
Non-Aqueous Base    q.s.


  • Vitiligo
  • Psoriasis
  • Atopic Dermatitis


  • Methoxasalen the most effective psoralen derivative used in vitiligo and psoriasis, which acts as photosensitizer. Works by making the skin more sensitive to UVA light
  • Most common recommended treatment for vitiligo is methoxsalen followed by exposure to solar radiation or UVA radiation

As directed by the physician

Dosage Guidelines:
Vitiligo Theraphy

Drug Dosage: Two capsules (10 mg each) in one dose taken with milk or in food two to four hours before ultraviolet light exposure.
Light Exposure: The exposure time to sunlight should comply with the following guide:

Basic Skin Color    Light    Medium    Dark
Initial Exposure        15 min    20 min    25 min
Second Exposure      20 min    25 min    30 min
Third Exposure         25 min    30 min    35 min
Fourth Exposure       30 min    35 min    40 min

Subsequent Exposure: Gradually increase exposure based on erythema and tenderness of the amelanotic skin.Therapy should be on alternate days and never two consecutive days.

Psoriasis Theraphy
Drug Dosage - Initial Theraphy: The methoxsalen capsules should be taken 2 hours before UVA exposure with some food or milk according to the following table:

Patient's Weight    Dose
(kg)      (lbs.)            (mg)
<30      <66              10
30-50    66-110         20
51-65    112-143       30
66-80    146-176       40
81-90    179-198       50
91-115   201-254      60
>115    >254            70

Additional drug dosage directions are as follows:

  • Weight Change: In the event that the weight of a patient changes during treatment such that he/she falls into an adjacent weight range/dose category, no change in the dose of methoxsalen is usually required. If, in the physician's opinion, however, a weight change is sufficiently great to modify the drug dose, then an adjustment in the time of exposure to UVA should be made
  • Dose/Week: The number of doses per week of methoxsalen capsules will be determined by the patient's schedule of UVA exposures. In no case should treatments be given more often than once every other day because the full extent of phototoxic reactions may not be evident until 48 hours after each exposure
  • Dosage Increase: Dosage may be increased by 10 mgm after the fifteenth treatment

Salen Topical Solution – 25 ml bottle
Salen Capsules – 3 X 10 capsules

Note: To be used only on the advice of a Registered Medical Practitioner.

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